
Balsalazide disodium salt dihydrate
CAS No. 150399-21-6
Balsalazide disodium salt dihydrate ( Balsalazide Disodium | balsalazide | BX 661A | Colazal | Colazide )
产品货号. M18055 CAS No. 150399-21-6
Balsalazide 是一种抗炎化合物,用于治疗炎症性肠病。Balsalazide 是一种新的含有 5-氨基水杨酸 (5-ASA) 的前药。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
25MG | ¥1061 | 有现货 |
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100MG | ¥2454 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Balsalazide disodium salt dihydrate
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Balsalazide 是一种抗炎化合物,用于治疗炎症性肠病。Balsalazide 是一种新的含有 5-氨基水杨酸 (5-ASA) 的前药。
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产品描述Balsalazide Disodium is the disodium salt form of balsalazide, an aminosalicylate and oral prodrug that is enzymatically cleaved in the colon to produce the anti-inflammatory agent mesalazine. Mesalazine acts locally on the mucosa of the colon where it diminishes inflammation by blocking the production of arachidonic acid metabolites and other inflammatory agents. Balsalazide disodium is used to treat chronic inflammatory bowel disease.(In Vivo):At the endpoint, the protein production of MIP-1β, MCP-1, IL-6, and IL-10 in the colon tissues decrease in concordance with the plasma concentrations of the cytokines. The drug-treated groups reveal lower expression of p-STAT3 compared to the CAC group. In addition, BCL2 decreases and BAX increases markedly in the BSZ+VSL#3 group. Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing prodrug.
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体外实验——
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体内实验At the endpoint, the protein production of MIP-1β, MCP-1, IL-6, and IL-10 in the colon tissues decrease in concordance with the plasma concentrations of the cytokines. The drug-treated groups reveal lower expression of p-STAT3 compared to the CAC group. In addition, BCL2 decreases and BAX increases markedly in the BSZ+VSL#3 group. Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing prodrug.
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同义词Balsalazide Disodium | balsalazide | BX 661A | Colazal | Colazide
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通路Others
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靶点Other Targets
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受体STAT
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研究领域Inflammation/Immunology
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适应症——
化学信息
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CAS Number150399-21-6
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分子量437.31
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分子式C17H17N3Na2O8
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (285.84 mM)
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SMILES[Na+].[Na+].O.O.O=C([O-])c1cc(ccc1O)/N=N/c2ccc(cc2)C(=O)NCCC([O-])=O
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化学全称5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic Acid Disodium Salt Dihydrate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献




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